Biocept Launches Selector(TM), a Blood Based Test for EGFR Mutations for Non-Small Cell Lung Cancer Patients
Approximately 20 percent of the NSCLC cases diagnosed each year are identified as EGFR-mutant, a correlation which has led to a number of targeted therapies focused on the patient population whose tumor has this mutation. These targeted therapies are known as Tyrosine Kinase Inhibitors, or TKIs. TKIs have been shown to be effective at shrinking tumors for a time, however, many patients ultimately develop resistance to EGFR-targeted TKIs because of secondary mutations such as T790M. Evaluating and monitoring for these secondary mutations in a clinical setting utilizing a blood sample could enhance the way treatment is managed. In addition to better informing clinicians when and how to treat NSCLC with TKIs, there are promising new therapies in clinical testing that target resistance alterations like T790M.
"Monitoring for EGFR resistance mutations in ctDNA from patients being treated with TKIs has the potential to dramatically change how physicians treat patients," said
"In addition to being a noninvasive method to collect tumor related samples, blood testing could overcome the frequent obstacle of lack of sufficient tissue for molecular testing as well as issues with tumor heterogeneity. We believe these are significant advantages to our technology when testing gene mutations such as T790M," Singh said.
"We are excited to launch our first test using our proprietary Selector technology," said
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